Rejuran

Hydrolyzed DNA technology that supports collagen, elasticity, hydration, and the skin barrier.

About Rejuran

Rejuran is an advanced skin-repair treatment that uses hydrolyzed DNA technology to support collagen, improve elasticity, boost hydration, reduce inflammation, and strengthen the skin barrier. It can be used as a standalone series or layered with other treatments for deeper rejuvenation.

Best For

  • Skin repair
  • Barrier support
  • Fine lines
  • Elasticity
  • Post-procedure recovery
  • Hydration

Why Rejuran

  • DOT (DNA Optimizing Technology) using hydrolyzed salmon DNA
  • Korea’s #1 injectable, now available in NYC
  • Promotes collagen, elasticity, hydration, and skin healing
  • Layered post-procedure or infused as a standalone treatment
  • Strengthens skin barrier and reduces inflammation

How It Works

  1. 01

    Procedure Prep

    Skin is pre-treated with microneedling, peel, RF, or laser depending on the protocol — or cleansed for direct infusion.

  2. 02

    Rejuran Application

    Booster is layered onto skin after the prep procedure, or Healing Essence is infused for direct delivery.

  3. 03

    Series Build

    Recommended series of 3 infusions spaced 6 weeks apart. Layering boosters can be used after any compatible procedure.

What to Expect

  • Application after another procedure (layering)
  • Direct infusion via Glowpin or syringe
  • Mild redness for hours after layering; pinpoint marks for direct infusion
  • Visible improvement after each session
  • Best results from a series of 3 infusions

Pricing

Rejuran is offered in two formats: layering boosters that are applied after another procedure, or direct infusion of Healing Essence as a standalone treatment. The infusion protocol is a series of 3 sessions spaced 6 weeks apart.

Skin Layering

Applied after microneedling, chemical peel, laser, or Morpheus/Fractora

  • Healing Essence 2% PN — the Korean #1 injectable, layered post-procedure
    $250
  • Rejuran Skin Booster 1% PN — cPDRN, amino acids, HA
    $100
  • Tone-Up Booster 1% PN — brightening with L-ascorbic, glutathione, tranexamic
    $100
  • Healing Essence + Booster Combined layering protocol
    $300

Direct Infusion

Healing Essence delivered by injection or via Glowpin Infusion

  • 1 Syringe Per session, single syringe
    $850
  • 2 Syringes Per session, double dose
    $1,600
Recommended Protocol

A series of 3 infusions spaced 6 weeks apart is advised for optimal results. FDA approval for direct injection is pending in the US, but off-label use can be discussed with your dermatologist.

Frequently Asked Questions

What’s PN/PDRN?

PN (polynucleotide) and PDRN (polydeoxyribonucleotide) are hydrolyzed DNA fragments derived from wild salmon. They activate skin-repair pathways, support collagen production, improve elasticity, and reduce inflammation.

Is direct injection of Rejuran FDA-approved?

Direct injection is widely used internationally and is awaiting FDA approval in the US. Off-label use can be discussed with your dermatologist. Layering boosters are routinely used with FDA-approved procedures.

What’s the difference between Healing Essence and Booster?

Healing Essence is the higher-concentration formulation (2% PN) used either layered post-procedure or infused. The Booster is a 1% PN formulation designed for layering after any compatible procedure for hydration and barrier support.

How is Rejuran different from PRP?

Both stimulate skin healing and collagen. PRP uses your own platelets and growth factors. Rejuran uses standardized hydrolyzed salmon DNA that consistently activates skin-repair pathways. Many patients use both at different times.

How many sessions do I need?

For direct infusion, a series of 3 sessions spaced 6 weeks apart is advised. Layering boosters can be added to any compatible procedure as desired.

Can Rejuran be combined with other treatments?

Yes — Rejuran pairs naturally with microneedling, chemical peels, lasers, RF microneedling, and other procedures. The boosters are designed specifically for post-procedure layering.

When will I see Rejuran results?

Subtle improvements in glow and hydration are often visible after the first session. Full results develop over 3 months as collagen rebuilds.

Support your skin from the inside out.

Schedule a consultation with one of our board-certified dermatologists in Tribeca.

Book a Consultation