Injectable Biostimulators

Stimulate your skin’s own collagen for natural, gradual rejuvenation — with Sculptra and Hyperdilute Radiesse.

About Injectable Biostimulators

Injectable biostimulators trigger your body’s own collagen production rather than placing volume in the skin. We offer Sculptra and Hyperdilute Radiesse — two biostimulators that work gradually over weeks and months to firm, smooth, and rebuild structure lost with age.

Best For

  • Skin laxity
  • Crepey skin
  • Volume restoration
  • Cheeks
  • Temples
  • Décolleté
  • Neck
  • Hands
  • Long-term collagen support

Products We Use

Each biostimulator works through a different mechanism. Your dermatologist will help select the right product based on the area being treated and your goals.

Sculptra Poly-L-lactic acid · Galderma
Hyperdilute Radiesse Calcium hydroxylapatite · Merz Aesthetics

How It Works

  1. 01

    Consultation

    Your dermatologist evaluates your concerns, anatomy, and goals to recommend the right biostimulator, treatment area, and series.

  2. 02

    Treatment

    Sculptra or Hyperdilute Radiesse is placed precisely with a fine needle or cannula. Topical numbing keeps you comfortable; most appointments take 30 to 45 minutes. Sculptra patients massage the treated area daily for several days afterward.

  3. 03

    Results

    Results build gradually over 2 to 3 months as your body produces new collagen. A series of 2 to 3 sessions, spaced 4 to 6 weeks apart, is typical. Final results can last 18 to 24 months or longer.

What to Expect

  • Gradual, natural-looking results that build over 2 to 3 months
  • A series of 2 to 3 sessions is typical for optimal results
  • Long-lasting — 18 to 24 months or longer
  • Stimulates your body’s own collagen rather than adding material
  • Minimal downtime — mild swelling or bruising possible
  • Not reversible — conservative dosing and product selection are essential
  • Performed by board-certified dermatologists

Pricing

Sculptra and Hyperdilute Radiesse are priced separately based on the product and treatment plan. A series of sessions is typical for optimal results.

Sculptra

  • One vial $1,000
  • Two vials $2,000

A series of 2 to 3 sessions, spaced 4 to 6 weeks apart, is typically recommended for full results.

Hyperdilute Radiesse

  • Single Treatment Per site — face, neck, or chest
    $1,250
  • Package of 3 Sessions One site
    $3,000
  • Package of 3 Sessions Two sites
    $6,000

Frequently Asked Questions

What’s the difference between biostimulators and traditional dermal fillers?

Traditional fillers (such as Juvederm, Restylane, RHA, and Belotero) place hyaluronic acid or calcium-based gel directly into the skin to add immediate volume. Biostimulators work differently — rather than acting as fillers themselves, Sculptra and Hyperdilute Radiesse stimulate your body to produce new collagen over weeks and months. The result is more gradual, but the effect is your own tissue rather than placed product.

What is the difference between Sculptra and Hyperdilute Radiesse?

Sculptra (poly-L-lactic acid) is best for restoring deep volume in areas of fat loss — especially the cheeks, temples, and lower face — and is also used for body indications like the décolleté and buttocks. Hyperdilute Radiesse uses Radiesse (calcium hydroxylapatite) diluted with saline and lidocaine, creating a thinner consistency optimized for skin tightening and treating crepey, lax skin on the décolleté, neck, hands, and arms. Your dermatologist will recommend the right product based on your concern.

When will I see results?

Biostimulators work gradually. You may notice initial smoothing within a few weeks as the product stimulates collagen, but final results typically build over 2 to 3 months and continue to improve as new collagen forms. Most patients require a series of 2 to 3 sessions spaced 4 to 6 weeks apart for optimal results.

How long do results last?

Once your full series is complete, results from Sculptra and Hyperdilute Radiesse can last 18 to 24 months or longer. Maintenance treatments are typically recommended once a year or every other year to preserve the collagen-building effect.

Can biostimulators be combined with traditional fillers or wrinkle relaxers?

Yes. Biostimulators are often combined with hyaluronic acid fillers, wrinkle relaxers, and energy-based treatments to create a comprehensive plan. Sculptra restores deep volume and structure; HA fillers refine specific contours; wrinkle relaxers soften expression lines — together they address different layers of aging.

Are biostimulators reversible?

No. Unlike hyaluronic acid fillers (which can be dissolved with hyaluronidase), biostimulators trigger your body’s own collagen production, which cannot be reversed. This is why product selection, conservative dosing, and an experienced injector are essential.

Is there any downtime?

Most patients return to normal activities the same day. Mild swelling, redness, or bruising at injection sites is common and typically resolves within 3 to 7 days. Sculptra patients are asked to massage the treated area for several days following injection to support even product distribution. We recommend avoiding strenuous exercise and alcohol for 24 hours.

Is it painful?

Most patients tolerate biostimulator injections well. Topical numbing cream is applied before treatment, and Hyperdilute Radiesse contains lidocaine for added comfort during injection. Sessions are typically described as mildly uncomfortable rather than painful.

Ready to find the right filler for you?

Schedule a consultation with one of our board-certified dermatologists in Tribeca.

Book a Consultation